VIB spin-off MRM Health reports positive preclinical results in non-alcoholic fatty liver disease
June 7, 2022
MRM Health is a VIB spin-off founded in 2020 by Sam Possemiers in a joint venture with VIB. Using a 9-strain bacterial consortium, MRM Health’s laboratories led by Dr. Salvador Augustin and Dr. Maria Martell of the University Hospital of Vall d’Hebron were able to slow down disease progression in Non-Alcoholic Fatty Liver Disease (NAFLD). Preclinical results show that a live bacterial consortium of 9 rationally selected gut commensal strains were able to improve portal hypertension, insulin signaling, and NAFLD activity score. Additionally, the consortium helped prevent fibrosis development in two different in vivo disease models of Non-Alcoholic Steatohepatitis (NASH), improving endothelial functions and rebalancing the gut microbiome.
